Supplements

Find what helps your specific symptoms — honest evidence grades on every supplement. No agenda. No commissions.

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Showing all 80 supplements
Mineral
Strong
Calcium
Multiple randomized trials confirm calcium supplementation helps preserve bone mass a...
Supplement
Strong
Creatine
Creatine has decades of robust research showing it helps preserve muscle mass and str...
Supplement
Strong
Omega-3 Fatty Acids
Omega-3 fatty acids have strong evidence for protecting your heart during menopause w...
Peptide
Strong
PT-141 / Bremelanotide (Peptide)
PT-141 (bremelanotide) is FDA-approved as Vyleesi and represents one of the few treat...
Vitamin
Strong
Vitamin B12
B12 deficiency affects up to 20% of women over 40 and can convincingly mimic menopaus...
Vitamin
Strong
Vitamin C
Vitamin C provides solid foundational support during menopause, with strong evidence ...
Vitamin
Strong
Vitamin D3
Vitamin D3 has strong evidence for protecting bone health during menopause, with mult...
Vitamin
Strong
Vitamin K2 (MK-7)
Vitamin K2 MK-7 demonstrates strong evidence for reducing bone fractures in postmenop...
Supplement
Mixed
5-HTP
5-HTP shows promising results for mood and sleep during menopause, with several small...
Supplement
Mixed
Acetyl-L-Carnitine (ALCAR)
Acetyl-L-carnitine shows promising results for mental clarity and cognitive function ...
Supplement
Mixed
Akkermansia Muciniphila
Akkermansia muciniphila is a beneficial gut bacteria that helps maintain intestinal b...
Supplement
Mixed
Alpha Lipoic Acid
Alpha-lipoic acid shows solid evidence for improving insulin sensitivity and supporti...
Adaptogen
Mixed
Ashwagandha
Ashwagandha shows solid evidence for reducing cortisol levels and improving stress re...
Peptide
Mixed
BPC-157 (Peptide)
BPC-157 shows remarkable tissue healing effects in animal studies, particularly for t...
Supplement
Mixed
Berberine
Berberine demonstrates robust evidence for improving blood sugar control and insulin ...
Supplement
Mixed
Bifidobacterium Probiotics
Bifidobacterium probiotics show promise for digestive comfort, mood support, and slee...
Herb
Mixed
Black Cohosh
Black cohosh has the strongest research backing of any herb for hot flashes, with wel...
Mineral
Mixed
Boron
Boron helps your body use calcium and vitamin D more effectively, with small studies ...
Supplement
Mixed
Chondroitin Sulphate
Chondroitin sulfate shows modest benefits for joint pain in several studies, with eff...
Mineral
Mixed
Chromium
Chromium shows modest promise for stabilizing blood sugar and reducing the carb cravi...
Supplement
Mixed
CoQ10 (Ubiquinone)
Some studies suggest CoQ10 may help with energy, heart health, and reducing oxidative...
Supplement
Mixed
CoQ10 Ubiquinol
CoQ10 has solid evidence for supporting heart health and may help with fatigue, thoug...
Supplement
Mixed
Collagen Peptides
Collagen peptides show solid evidence for improving skin hydration and elasticity, ad...
Supplement
Mixed
DHEA
DHEA shows its strongest evidence for sexual function in menopause, with FDA-approved...
Supplement
Mixed
DIM (Diindolylmethane)
DIM from cruciferous vegetables shows early promise for supporting how your body proc...
Supplement
Mixed
Fisetin
Fisetin, a flavonoid abundant in strawberries and apples, shows early promise for cel...
Vitamin
Mixed
Folate (Vitamin B9)
Folate supports mood stability and DNA repair, both crucial as estrogen declines duri...
Peptide
Mixed
GHK-Cu (Copper Peptide)
GHK-Cu shows solid evidence for improving skin firmness, elasticity, and reducing fin...
Herb
Mixed
Ginkgo Biloba
Ginkgo biloba shows promise for improving circulation and mental clarity, with severa...
Supplement
Mixed
Glucosamine
Glucosamine sulfate shows modest but consistent benefits for knee osteoarthritis pain...
Supplement
Mixed
Glutathione
Glutathione, your body's master antioxidant, naturally declines during menopause when...
Supplement
Mixed
Glycine
Glycine shows consistent promise for sleep quality, with multiple small studies findi...
Herb
Mixed
Holy Basil (Tulsi)
Holy basil shows promise for reducing cortisol levels and supporting stress resilienc...
Supplement
Mixed
Hyaluronic Acid
Hyaluronic acid shows promising evidence for improving skin hydration and reducing jo...
Mineral
Mixed
Iodine
Iodine supports thyroid function, which directly impacts metabolism, energy, and brai...
Peptide
Mixed
Ipamorelin (Peptide)
Ipamorelin is a prescription peptide that stimulates growth hormone release, which na...
Mineral
Mixed
Iron
Iron deficiency is remarkably common during perimenopause due to heavy bleeding, and ...
Supplement
Mixed
L-Glutamine
L-glutamine may help strengthen the gut barrier that estrogen decline tends to weaken...
Supplement
Mixed
L-Theanine
L-theanine shows consistent evidence for reducing anxiety and promoting better sleep ...
Supplement
Mixed
L-Tryptophan
L-tryptophan shows modest but consistent benefits for sleep quality in several trials...
Supplement
Mixed
Lactobacillus Probiotics
Lactobacillus probiotics show promise for vaginal health and digestive comfort during...
Herb
Mixed
Lemon Balm
Lemon balm shows promise for easing anxiety and improving sleep quality in several sm...
Herb
Mixed
Lions Mane Mushroom
Lion's mane mushroom contains hericenones and erinacines that may support nerve growt...
Supplement
Mixed
MSM (Methylsulfonylmethane)
MSM shows modest promise for reducing joint pain and stiffness, with several small st...
Adaptogen
Mixed
Maca Root
Maca root shows modest promise for hot flashes and sexual function in small studies o...
Mineral
Mixed
Magnesium
Magnesium shows solid evidence for improving sleep quality and reducing muscle cramps...
Mineral
Mixed
Magnesium Glycinate
Magnesium glycinate shows promise for improving sleep quality and reducing anxiety in...
Mineral
Mixed
Magnesium Malate
Magnesium malate pairs well-established magnesium benefits with malic acid for potent...
Supplement
Mixed
Melatonin
Melatonin consistently improves sleep quality during menopause across multiple studie...
Supplement
Mixed
NAC (N-Acetyl Cysteine)
NAC shows promising evidence for anxiety and intrusive thoughts, with several randomi...
Supplement
Mixed
NMN (Nicotinamide Mononucleotide)
NMN may help restore cellular energy by boosting NAD+ levels, which decline with age ...
Supplement
Mixed
NR (Nicotinamide Riboside)
NR shows promise for supporting cellular energy production and may help with cognitiv...
Supplement
Mixed
PQQ (Pyrroloquinoline Quinone)
PQQ shows modest promise for supporting cellular energy production and may help with ...
Adaptogen
Mixed
Panax Ginseng
Panax ginseng shows meaningful promise for menopausal fatigue and hot flashes, with s...
Herb
Mixed
Passionflower
Passionflower shows genuine promise for anxiety and sleep troubles that often spike d...
Supplement
Mixed
Phosphatidylserine
Phosphatidylserine shows promise for memory support and stress response in small stud...
Supplement
Mixed
Quercetin
Quercetin shows promising evidence for reducing inflammation and supporting cardiovas...
Herb
Mixed
Red Clover
Red clover contains isoflavones that weakly mimic estrogen. Mixed evidence for hot fl...
Supplement
Mixed
Resveratrol
Small studies suggest resveratrol may support heart health and bone density during me...
Adaptogen
Mixed
Rhodiola Rosea
Rhodiola shows solid evidence for helping your body handle stress and mental fatigue,...
Mineral
Mixed
Selenium
Selenium supports thyroid hormone conversion and shows modest benefits for thyroid an...
Adaptogen
Mixed
Shatavari
Shatavari shows modest promise for reducing hot flash frequency and improving sleep q...
Supplement
Mixed
Spermidine
Spermidine supports autophagy, your body's cellular recycling system that naturally s...
Herb
Mixed
St John's Wort
St John's Wort shows solid evidence for mild to moderate depression, performing compa...
Supplement
Mixed
Sulforaphane
Sulforaphane shows strong evidence for supporting your body's natural detoxification ...
Supplement
Mixed
Taurine
Taurine shows solid promise for cardiovascular health during menopause, when heart di...
Supplement
Mixed
Urolithin A
Small human studies suggest urolithin A may improve muscle strength and mitochondrial...
Herb
Mixed
Valerian Root
Valerian root shows modest evidence for helping you fall asleep faster and improving ...
Vitamin
Mixed
Vitamin B6 (Pyridoxine)
B6 supports production of serotonin and dopamine, neurotransmitters that plummet duri...
Vitamin
Mixed
Vitamin E (Mixed Tocopherols)
Vitamin E shows modest promise for reducing hot flash frequency and intensity in smal...
Herb
Mixed
Vitex (Chaste Tree Berry)
Vitex shows solid evidence for easing PMS symptoms and may help support hormone balan...
Mineral
Mixed
Zinc
Zinc shows promising benefits for hair thinning and skin health during menopause, wit...
Supplement
Weak
Calcium D-Glucarate
Calcium D-glucarate supports your liver's natural detoxification process for clearing...
Herb
Weak
Dong Quai
Dong quai shows modest promise in small studies when combined with other herbs for ho...
Peptide
Weak
Epithalon (Peptide)
Epithalon, a synthetic peptide, has shown promise for improving sleep quality and cel...
Supplement
Weak
Evening Primrose Oil
Evening primrose oil is widely marketed for menopause symptoms. The evidence for hot ...
Supplement
Weak
GABA
GABA supplements show modest promise for sleep quality and evening anxiety in small s...
Supplement
Weak
Pregnenolone
Pregnenolone is a hormone precursor that your body uses to make progesterone, DHEA, a...
Herb
Weak
Sage
Sage has been used traditionally for hot flash relief. Evidence is limited but some s...
Mineral
Weak
Silica (Silicon)
Silica supports collagen production and connective tissue health, with small studies ...